CGRP antibody (Middle Region)

Catalog No. ABIN951490

Product Details anti-CGRP Antibody

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Binding Specificity: AA 63-91, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CGRP antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CALCA.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human CALCA

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CGRP

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Alternative Name: CGRP / CALCA (CALCA Products)

Synonyms: CALC1 antibody, CGRP antibody, CGRP-I antibody, CGRP1 antibody, CT antibody, KC antibody, CALC antibody, CALCA antibody, CALC3 antibody, ci-ct antibody, calca antibody, CA antibody, CGRP-1 antibody, Calc antibody, Calc1 antibody, Cgrp antibody, Ct antibody, Ctn antibody, calcitonin antibody, CAL6 antibody, Cal1 antibody, RATCAL6 antibody, CGRPI antibody, calc antibody, cgrp antibody, zgc:92886 antibody, calcitonin related polypeptide alpha antibody, calcitonin related polypeptide beta antibody, calcitonin-related polypeptide alpha antibody, calcitonin antibody, calcitonin/calcitonin-related polypeptide, alpha antibody, calcitonin-related polypeptide beta antibody, calcitonin gene-related peptide 2 antibody, CALCA antibody, CALCB antibody, ci-ct antibody, calca antibody, Calca antibody, LOC100008771 antibody

Background: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Alpha-type CGRP, CALC1, CGRP-I, Calcitonin gene-related peptide I

Molecular Weight: 13898 Da

Gene ID: 796

NCBI Accession: NP_001029125

Pathways: Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour