Claudin 4 (CLDN4) (AA 177-206), (C-Term) antibody

Details for Product No. ABIN951550, Supplier: Log in to see
Antigen
  • CLDN4
  • cper
  • cpe-r
  • cpetr
  • cpetr1
  • hcpe-r
  • wbscr8
  • CPE-R
  • CPER
  • CPETR
  • CPETR1
  • WBSCR8
  • hCPE-R
  • Cep-r
  • Cpetr
  • Cpetr1
  • claudin 4
  • claudin-4-like
  • claudin 4-like
  • RIKEN cDNA 4930412D23 gene
  • similar to claudin 4
  • CLDN4
  • LOC100059948
  • cldn4
  • Cldn4
  • LOC100340963
  • LOC100856416
  • 4930412D23Rik
  • LOC688420
Alternatives
anti-Mouse (Murine) Claudin 4 antibody for ELISA
Epitope
C-Term, AA 177-206
59
17
15
10
7
3
3
3
2
2
1
1
1
Reactivity
Human, Mouse (Murine)
139
75
45
5
5
4
4
2
2
1
Host
Rabbit
113
28
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
72
54
38
36
21
13
12
5
4
2
2
Options
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Immunogen KLH conjugated synthetic peptide between 177~206 amino acids from the C-terminal region of human CLDN4
Isotype Ig
Specificity This antibody reacts to CLDN4.
Cross-Reactivity (Details) Species reactivity (tested):Human and Mouse.
Purification Affinity chromatography on Protein A
Alternative Name Claudin-4 / CLDN4 (CLDN4 Antibody Abstract)
Background CLDN4 is an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life.Synonyms: CPE-R, CPE-Receptor, CPER, CPETR1, Clostridium perfringens enterotoxin receptor, WBSCR8, Williams-Beuren syndrome chromosomal region 8 protein
Molecular Weight 22077 Da
Gene ID 1364
NCBI Accession NP_001296
Research Area Cytoskeleton
Pathways Hepatitis C
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Claudin 4 (CLDN4) (AA 177-206), (C-Term) antibody (ABIN951550) Western blot analysis of CLDN4 Antibody (C-term) in mouse heart tissue lysates ...
Background publications Papageorgis, Lambert, Ozturk, Gao, Pan, Manne, Alekseyev, Thiagalingam, Abdolmaleky, Lenburg, Thiagalingam: "Smad signaling is required to maintain epigenetic silencing during breast cancer progression." in: Cancer research, Vol. 70, Issue 3, pp. 968-78, 2010 (PubMed).

Seckin, Arici, Harputluoglu, Yonem, Yilmaz, Ozer, Karincaoglu, Demirel: "Expression of claudin-4 and beta-catenin in gastric premalignant lesions." in: Acta gastro-enterologica Belgica, Vol. 72, Issue 4, pp. 407-12, 2010 (PubMed).

Kimura, Abe, Kamitani, Toshima, Fukui, Miyake, Kamata, Sugita-Konishi, Yamamoto, Horiguchi: "Clostridium perfringens enterotoxin interacts with claudins via electrostatic attraction." in: The Journal of biological chemistry, Vol. 285, Issue 1, pp. 401-8, 2009 (PubMed).

Robertson, Smedley, McClane: "Identification of a claudin-4 residue important for mediating the host cell binding and action of Clostridium perfringens enterotoxin." in: Infection and immunity, Vol. 78, Issue 1, pp. 505-17, 2009 (PubMed).