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C-Type Lectin Domain Family 2, Member A (CLEC2A) (AA 79-107), (Middle Region) antibody

Details for Product No. ABIN951564, Supplier: Log in to see
Antigen
  • KACL
  • PILAR
  • UNQ5792
Epitope
AA 79-107, Middle Region
16
13
8
8
5
2
Reactivity
Human
34
1
1
Host
Rabbit
26
8
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
23
19
8
2
2
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CLEC2A
Isotype Ig
Specificity This antibody reacts to CLEC2A.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CLEC2A (CLEC2A Antibody Abstract)
Background CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).Synonyms: C-type lectin domain family 2 member A
Molecular Weight 19972 Da
Gene ID 387836
NCBI Accession NP_001124183
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-C-Type Lectin Domain Family 2, Member A (CLEC2A) (AA 79-107), (Middle Region) antibody (ABIN951564) CLEC2A Antibody (Center) western blot analysis in HL-60 cell line lysates (35µg...
Background publications Spreu, Kuttruff, Stejfova, Dennehy, Schittek, Steinle: "Interaction of C-type lectin-like receptors NKp65 and KACL facilitates dedicated immune recognition of human keratinocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 11, pp. 5100-5, 2010 (PubMed).

Ozaki, Suzuki-Inoue, Inoue: "Novel interactions in platelet biology: CLEC-2/podoplanin and laminin/GPVI." in: Journal of thrombosis and haemostasis : JTH, Vol. 7 Suppl 1, pp. 191-4, 2009 (PubMed).

Rerkasem, Gallagher, Grimble, Calder, Shearman: "Managing hypercholesterolemia and its correlation with carotid plaque morphology in patients undergoing carotid endarterectomy." in: Vascular health and risk management, Vol. 4, Issue 6, pp. 1259-64, 2009 (PubMed).

Spreu, Kienle, Schrage, Steinle: "CLEC2A: a novel, alternatively spliced and skin-associated member of the NKC-encoded AICL-CD69-LLT1 family." in: Immunogenetics, Vol. 59, Issue 12, pp. 903-12, 2007 (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).