Copine III (CPNE3) (AA 506-533), (C-Term) antibody

Details for Product No. ABIN951661, Supplier: Log in to see
Antigen
  • MGC55622
  • zgc:55622
  • MGC79464
  • MGC130669
  • CPN3
  • PRO1071
  • 5430428M23Rik
  • 5730450C07Rik
  • C85108
  • Copine-3
  • copine III
  • cpne3
  • CPNE3
  • Cpne3
Epitope
C-Term, AA 506-533
12
10
8
4
2
2
2
2
1
1
1
Reactivity
Human
38
8
4
2
1
Host
Rabbit
33
5
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
36
19
8
5
1
1
1
Options
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Immunogen KLH conjugated synthetic peptide between 506-533 amino acids from the C-terminal region of Human CPNE3. Genename: CPNE3
Isotype Ig
Specificity This antibody recognizes Human Copine-3 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name Copine-3 (CPNE3 Antibody Abstract)
Background Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a protein which contains two type II C2 domains in the amino-terminus and an A domain-like sequence in the carboxy-terminus. The A domain mediates interactions between integrins and extracellular ligands.Synonyms: CPN3, CPNE3, Copine III, KIAA0636
Molecular Weight 60131 Da
Gene ID 8895
NCBI Accession NP_003900
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Copine III (CPNE3) (AA 506-533), (C-Term) antibody (ABIN951661) Western blot analysis of Copine-3 Antibody (C-term) in 293 cell line lysates (35ug/la...
Background publications Heinrich, Keller, Boulay, Vecchi, Bianchi, Sack, Lienhard, Duss, Hofsteenge, Hynes: "Copine-III interacts with ErbB2 and promotes tumor cell migration." in: Oncogene, Vol. 29, Issue 11, pp. 1598-610, 2010 (PubMed).

Thomas, Jacobs, Yeager, Kraft, Wacholder, Orr, Yu, Chatterjee, Welch, Hutchinson, Crenshaw, Cancel-Tassin, Staats, Wang, Gonzalez-Bosquet, Fang, Deng, Berndt, Calle, Feigelson, Thun, Rodriguez, Albanes, Virtamo, Weinstein, Schumacher, Giovannucci, Willett: "Multiple loci identified in a genome-wide association study of prostate cancer." in: Nature genetics, Vol. 40, Issue 3, pp. 310-5, 2008 (PubMed).

Cowland, Carter, Bjerregaard, Johnsen, Borregaard, Lollike: "Tissue expression of copines and isolation of copines I and III from the cytosol of human neutrophils." in: Journal of leukocyte biology, Vol. 74, Issue 3, pp. 379-88, 2003 (PubMed).

Caudell, Caudell, Tang, Yu, Frederick, Grimm: "Characterization of human copine III as a phosphoprotein with associated kinase activity." in: Biochemistry, Vol. 39, Issue 42, pp. 13034-43, 2000 (PubMed).

Creutz, Tomsig, Snyder, Gautier, Skouri, Beisson, Cohen: "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans." in: The Journal of biological chemistry, Vol. 273, Issue 3, pp. 1393-402, 1998 (PubMed).