Copine III (CPNE3) (C-Term), (AA 506-533) antibody

Details for Product No. ABIN951661
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Antigen
Synonyms MGC55622, zgc:55622, MGC79464, MGC130669, CPN3, PRO1071, 5430428M23Rik, 5730450C07Rik, C85108, Copine-3
Epitope
C-Term, AA 506-533
(8), (7), (2), (2), (1), (1)
Reactivity
Human
(18), (4), (3)
Host
Rabbit
(16), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(19), (9), (4), (2), (2)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN951661
357.50 $
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Immunogen KLH conjugated synthetic peptide between 506-533 amino acids from the C-terminal region of Human CPNE3. Genename: CPNE3
Specificity This antibody recognizes Human Copine-3 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name Copine-3
Background Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a protein which contains two type II C2 domains in the amino-terminus and an A domain-like sequence in the carboxy-terminus. The A domain mediates interactions between integrins and extracellular ligands.
Alternate names: CPN3, CPNE3, Copine III, KIAA0636
Molecular Weight 60131 Da
Gene ID 8895
NCBI Accession NP_003900
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Creutz, Tomsig, Snyder et al.: "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans." in: The Journal of biological chemistry, Vol. 273, Issue 3, pp. 1393-402, 1998 (PubMed).

Caudell, Caudell, Tang et al.: "Characterization of human copine III as a phosphoprotein with associated kinase activity." in: Biochemistry, Vol. 39, Issue 42, pp. 13034-43, 2000 (PubMed).

Cowland, Carter, Bjerregaard et al.: "Tissue expression of copines and isolation of copines I and III from the cytosol of human neutrophils." in: Journal of leukocyte biology, Vol. 74, Issue 3, pp. 379-88, 2003 (PubMed).

Thomas, Jacobs, Yeager et al.: "Multiple loci identified in a genome-wide association study of prostate cancer." in: Nature genetics, Vol. 40, Issue 3, pp. 310-5, 2008 (PubMed).

Heinrich, Keller, Boulay et al.: "Copine-III interacts with ErbB2 and promotes tumor cell migration." in: Oncogene, Vol. 29, Issue 11, pp. 1598-610, 2010 (PubMed).

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