Emilin1 antibody

Catalog No. ABIN952077

Product Details anti-Emilin1 Antibody

Target: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Emilin1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Specificity: This antibody was selected for its ability to detect Murine Emilin-1.

Cross-Reactivity (Details): Species reactivity (tested):Mouse.

Purification: Affinity Chromatography on Protein G

Immunogen: Recombinant Mouse Emilin-1

Clone: C11A8

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration is 0.1-1.0 mg/mL. Centrifuge vial prior to opening.

Buffer: PBS

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C for one month or at -20 °C for longer. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Emilin1

Target: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Alternative Name: EMILIN1 (EMILIN1 Products)

Synonyms: im:7159005 antibody, si:dkey-20n10.2 antibody, wu:fc16f07 antibody, zgc:136949 antibody, EMILIN1 antibody, 5830419M17Rik antibody, AW229038 antibody, BB105748 antibody, EMILIN-1 antibody, gp115 antibody, EMI antibody, EMILIN antibody, elastin microfibril interfacer 1 antibody, elastin microfibril interfacer 1a antibody, elastin microfibril interfacer 1b antibody, elastin microfibril interfacer 1 L homeolog antibody, Emilin1 antibody, emilin1a antibody, emilin1b antibody, EMILIN1 antibody, emilin1.L antibody

Background: Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.Synonyms: EMI, EMILIN-1, Elastin microfibril interface-located protein 1, Elastin microfibril interfacer 1

Gene ID: 100952

NCBI Accession: NP_598679

UniProt: Q99K41