Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) (AA 467-495), (Middle Region) antibody

Details for Product No. ABIN952082
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Antigen
Synonyms
ECGP, GP96, TRA1, GRP94, TA-3, Tra1, gp96, ERp99, Targ2, Tra-1, endoplasmin, Grp94, tra1, tra-1, fb61d09, wu:fb61d09, wu:fq25g01, Gp96, ppk98, ecgp, grp94, hsp108, DDBDRAFT_0206450, DDBDRAFT_0215015,  ... show more
ECGP, GP96, TRA1, GRP94, TA-3, Tra1, gp96, ERp99, Targ2, Tra-1, endoplasmin, Grp94, tra1, tra-1, fb61d09, wu:fb61d09, wu:fq25g01, Gp96, ppk98, ecgp, grp94, hsp108, DDBDRAFT_0206450, DDBDRAFT_0215015, DDB_0206450, DDB_0215015 show less
Epitope
AA 467-495, Middle Region
(13), (8), (5), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(118), (60), (43), (41), (29), (22), (22), (11), (10), (8), (7), (7), (7), (6), (6), (2), (1), (1), (1)
Host
Rabbit
(91), (27), (24), (9)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
(118), (59), (44), (36), (35), (31), (23), (19), (10), (8), (4), (2)
Pubmed 2 references available
Catalog no. ABIN952082
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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Immunogen KLH conjugated synthetic peptide between 467-495 amino acids from the Central region of human HSP90B1
Specificity This antibody recognizes Human Endoplasmin / HSP90B1 / TRA1 (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name Endoplasmin / HSP90B1 / TRA1
Background HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1, MIM 140571) and mitochondria (TRAP1, MIM 606219) (Chen et al., 2005 [PubMed 16269234]).
Alternate names: 94 kDa glucose-regulated protein, GRP94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1
Molecular Weight 92469 Da
Gene ID 7184
NCBI Accession NP_003290
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Suzuki, Kulkarni: "Extracellular heat shock protein HSP90beta secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-beta1." in: Biochemical and biophysical research communications, Vol. 398, Issue 3, pp. 525-31, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Hosts (91), (27), (24), (9)
Reactivities (118), (60), (43), (41), (29), (22), (22), (11), (10), (8), (7), (7), (7), (6), (6), (2), (1), (1), (1)
Applications (118), (59), (44), (36), (35), (31), (23), (19), (10), (8), (4), (2)
Conjugates (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (8), (5), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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