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ERBB Receptor Feedback Inhibitor 1 (ERRFI1) (AA 256-286), (Middle Region) antibody

Details for Product No. ABIN952110
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Antigen
Synonyms MIG6, RALT, MIG-6, GENE-33, Mig6, Mig-6, AI788755, 1300002F13Rik, Xxx, Ralt, gene 33, RGD1307599, ERRFI1, fi40f02, MGC162129, wu:fi40f02
Epitope
AA 256-286, Middle Region
(7), (7), (6), (2), (2), (1), (1), (1)
Reactivity
Human
(39), (15), (15), (12), (12), (12), (12)
Host
Rabbit
(27), (12)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(29), (20), (10), (4), (3), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN952110
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 256-286 amino acids from the Central region of Human ERRFI1
Specificity This antibody recognizes Human ERRFI1 / MIG6 (Center).
Purification Affinity Chromatography on Protein A
Alternative Name ERRFI1 / MIG6
Background ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885], Fiorentino et al., 2000 [PubMed 11003669]).
Alternate names: ERBB receptor feedback inhibitor 1, Mitogen-inducible gene 6 protein
Molecular Weight 50560 Da
Gene ID 54206
NCBI Accession NP_061821
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Nagashima, Ushikoshi-Nakayama, Suenaga et al.: "Mutation of epidermal growth factor receptor is associated with MIG6 expression." in: The FEBS journal, Vol. 276, Issue 18, pp. 5239-51, 2009 (PubMed).

Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

Ying, Zheng, Scott et al.: "Mig-6 controls EGFR trafficking and suppresses gliomagenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 6912-7, 2010 (PubMed).

Frosi, Anastasi, Ballarò et al.: "A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation." in: The Journal of cell biology, Vol. 189, Issue 3, pp. 557-71, 2010 (PubMed).

Suelves, España-Gregori, Tembl et al.: "Doppler ultrasound and giant cell arteritis." in: Clinical ophthalmology (Auckland, N.Z.), Vol. 4, pp. 1383-4, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN952110
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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