ERBB Receptor Feedback Inhibitor 1 (ERRFI1) (AA 256-286), (Middle Region) antibody

Details for Product No. ABIN952110
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Synonyms ERRFI1, fi40f02, MGC162129, wu:fi40f02, GENE-33, MIG-6, MIG6, RALT, 1300002F13Rik, AI788755, Mig-6, Mig6, RGD1307599, Ralt, Xxx, gene 33, L36A, L44L, RPL44
AA 256-286, Middle Region
(15), (13), (3), (2), (2), (2), (1), (1), (1), (1), (1)
(33), (5), (5)
(27), (6)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(31), (20), (8), (3), (1)
Pubmed 5 references available
Quantity 0.4 mL
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Immunogen KLH conjugated synthetic peptide between 256-286 amino acids from the Central region of Human ERRFI1
Isotype Ig
Specificity This antibody recognizes Human ERRFI1 / MIG6 (Center).
Purification Affinity Chromatography on Protein A
Alternative Name ERRFI1 / MIG6 (ERRFI1 Antibody Abstract)
Background ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885], Fiorentino et al., 2000 [PubMed 11003669]).Synonyms: ERBB receptor feedback inhibitor 1, Mitogen-inducible gene 6 protein
Molecular Weight 50560 Da
Gene ID 54206
NCBI Accession NP_061821
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Suelves, España-Gregori, Tembl et al.: "Doppler ultrasound and giant cell arteritis." in: Clinical ophthalmology (Auckland, N.Z.), Vol. 4, pp. 1383-4, 2010 (PubMed).

Frosi, Anastasi, Ballarò et al.: "A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation." in: The Journal of cell biology, Vol. 189, Issue 3, pp. 557-71, 2010 (PubMed).

Ying, Zheng, Scott et al.: "Mig-6 controls EGFR trafficking and suppresses gliomagenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 6912-7, 2010 (PubMed).

Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

Nagashima, Ushikoshi-Nakayama, Suenaga et al.: "Mutation of epidermal growth factor receptor is associated with MIG6 expression." in: The FEBS journal, Vol. 276, Issue 18, pp. 5239-51, 2009 (PubMed).

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Catalog No. ABIN952110
$ 357.50
Plus shipping costs $45.00
0.4 mL
$ 357.50

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