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ERBB Receptor Feedback Inhibitor 1 (ERRFI1) (AA 256-286), (Middle Region) antibody

Details for Product No. ABIN952110, Supplier: Log in to see
Antigen
  • ERRFI1
  • fi40f02
  • MGC162129
  • wu:fi40f02
  • GENE-33
  • MIG-6
  • MIG6
  • RALT
  • 1300002F13Rik
  • AI788755
  • Mig-6
  • Mig6
  • RGD1307599
  • Ralt
  • Xxx
  • gene 33
  • L36A
  • L44L
  • RPL44
Alternatives
anti-Human ERBB Receptor Feedback Inhibitor 1 antibody for Western Blotting
Epitope
AA 256-286, Middle Region
8
6
4
2
2
2
2
1
1
Reactivity
Human
28
8
8
Host
Rabbit
22
6
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
23
16
8
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 256-286 amino acids from the Central region of Human ERRFI1
Isotype Ig
Specificity This antibody recognizes Human ERRFI1 / MIG6 (Center).
Purification Affinity Chromatography on Protein A
Alternative Name ERRFI1 / MIG6 (ERRFI1 Antibody Abstract)
Background ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885], Fiorentino et al., 2000 [PubMed 11003669]).Synonyms: ERBB receptor feedback inhibitor 1, Mitogen-inducible gene 6 protein
Molecular Weight 50560 Da
Gene ID 54206
NCBI Accession NP_061821
Pathways EGFR Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-ERBB Receptor Feedback Inhibitor 1 (ERRFI1) (AA 256-286), (Middle Region) antibody (ABIN952110) Western blot analysis of ERRFI1 / MIG6  Antibody  in HepG2 cell line lysates (35ug/la...
Background publications Suelves, España-Gregori, Tembl et al.: "Doppler ultrasound and giant cell arteritis." in: Clinical ophthalmology (Auckland, N.Z.), Vol. 4, pp. 1383-4, 2010 (PubMed).

Frosi, Anastasi, Ballarò et al.: "A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation." in: The Journal of cell biology, Vol. 189, Issue 3, pp. 557-71, 2010 (PubMed).

Ying, Zheng, Scott et al.: "Mig-6 controls EGFR trafficking and suppresses gliomagenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 6912-7, 2010 (PubMed).

Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

Nagashima, Ushikoshi-Nakayama, Suenaga et al.: "Mutation of epidermal growth factor receptor is associated with MIG6 expression." in: The FEBS journal, Vol. 276, Issue 18, pp. 5239-51, 2009 (PubMed).