F2RL2 antibody (N-Term)

Catalog No. ABIN952152

The Rabbit Polyclonal anti-F2RL2 antibody (ABIN952152) specifically detects F2RL2 in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for F2RL2 antibody (N-Term) (ABIN952152)

Target: F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F2RL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-F2RL2 Antibody

Binding Specificity: AA 20-50, N-Term

Specificity: This antibody recognizes Human F2RL2 (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of human F2RL2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for F2RL2

Target: F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))

Alternative Name: F2RL2

Background: Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.Synonyms: Coagulation factor II receptor-like 2, PAR-3, PAR3, Proteinase-activated receptor 3, Thrombin receptor-like 2

Molecular Weight: 42508 Da

Gene ID: 2151

NCBI Accession: NP_004092

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling