F-Box Protein 3 (FBXO3) (C-Term), (AA 401-431) antibody

Details for Product No. ABIN952286
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Antigen
Synonyms zgc:112485, DKFZp459H187, FBA, FBX3, 1200002G09Rik, 1700026K02Rik, AI046358, Fba
Epitope
C-Term, AA 401-431
(8), (7), (4), (2), (1)
Reactivity
Human
(16), (4), (4), (2), (1)
Host
Rabbit
(15), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB), Flow Cytometry (FACS)
(16), (9), (8), (1), (1)
Pubmed 2 references available
Quantity 0.4 mL
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Catalog No. ABIN952286
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Immunogen KLH conjugated synthetic peptide between 401~431 amino acids from the C-terminal region of human FBXO3.
Specificity This antibody recognizes Human FBXO3 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name FBXO3
Background FBXO3 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.
Alternate names: F-box only protein 3, FBX3
Molecular Weight 54561 Da
Gene ID 26273
NCBI Accession NP_036307
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Ilyin, Rialland, Pigeon et al.: "cDNA cloning and expression analysis of new members of the mammalian F-box protein family." in: Genomics, Vol. 67, Issue 1, pp. 40-7, 2000 (PubMed).

Shima, Shima, Chiba et al.: "PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation." in: Molecular and cellular biology, Vol. 28, Issue 23, pp. 7126-38, 2008 (PubMed).

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