FYVE, RhoGEF and PH Domain Containing 6 (FGD6) (C-Term), (AA 1331-1359) antibody

Details for Product No. ABIN952305
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Antigen
Synonyms ZFYVE24, AA123052, Etohd4
Epitope
C-Term, AA 1331-1359
(1)
Reactivity
Human
(2)
Host
Rabbit
(2)
Clonality
Polyclonal
Application
ELISA, Western Blotting (WB)
(2), (1), (1)
Pubmed 2 references available
Catalog no. ABIN952305
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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Immunogen KLH conjugated synthetic peptide between 1331-1359 amino acids from the C-terminal region of human FGD6
Specificity This antibody reacts to FGD6.
Purification Affinity chromatography on Protein A
Alternative Name FGD6
Background Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
Alternate names: FYVE, KIAA1362, RhoGEF and PH domain-containing protein 6, ZFYVE24, Zinc finger FYVE domain-containing protein 24
Gene ID 55785
NCBI Accession NP_060821
Research Area Signaling
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Jin, Smith, Stark et al.: "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization." in: Current biology : CB, Vol. 14, Issue 16, pp. 1436-50, 2004 (PubMed).

Barrios-Rodiles, Brown, Ozdamar et al.: "High-throughput mapping of a dynamic signaling network in mammalian cells." in: Science (New York, N.Y.), Vol. 307, Issue 5715, pp. 1621-5, 2005 (PubMed).

Hosts (2)
Reactivities (2)
Applications (2), (1), (1)
Epitopes (1)
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