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Fibulin 3 (FBLN3) (AA 126-156), (N-Term) antibody

Details for Product No. ABIN952326, Supplier: Log in to see
Antigen
  • DHRD
  • DRAD
  • FBLN3
  • FBNL
  • FIBL-3
  • MLVT
  • MTLV
  • S1-5
  • T16
  • EGF containing fibulin-like extracellular matrix protein 1
  • EGF-containing fibulin-like extracellular matrix protein 1
  • epidermal growth factor-containing fibulin-like extracellular matrix protein 1
  • EFEMP1
  • Efemp1
Alternatives
anti-Human Fibulin 3 antibody for Immunoprecipitation
Epitope
AA 126-156, N-Term
15
10
9
9
7
6
5
3
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
79
41
37
7
6
6
4
4
3
3
2
2
2
1
Host
Rabbit
73
11
Clonality
Polyclonal
Conjugate
Un-conjugated
5
5
2
2
2
2
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
81
47
27
14
13
12
8
6
3
3
2
1
Options
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Immunogen Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 126-156aa) of human Fibulin-3
Isotype Ig
Specificity This antibody recognizes Fibulin-3 at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse
Purification Purified through a Protein A column followed by peptide affinity purification
Alternative Name Fibulin-3 (FBLN3 Antibody Abstract)
Background EFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, Fibulin-3 contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors.Synonyms: DHRD, DRAD, EFEMP1, EGF-containing fibulin-like extracellular matrix protein 1, Extracellular protein S1-5, FBLN3, FBNL, Fibrillin-like protein, Fibulin 3, MLVT, MTLV, S1-5
Gene ID 2202
NCBI Accession NP_001034437
Pathways EGFR Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Fibulin 3 (FBLN3) (AA 126-156), (N-Term) antibody (ABIN952326) Flow cytometry analysis of NCI-H460 cells (bottom histogram) compared to a negative c...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Fibulin 3 (FBLN3) (AA 126-156), (N-Term) antibody (ABIN952326) Immunohistochemistry analysis in human lung carcinoma (Formalin-fixed, Paraffin-embed...
Western Blotting (WB) image for anti-Fibulin 3 (FBLN3) (AA 126-156), (N-Term) antibody (ABIN952326) Western blot analysis of Fibulin-3 (arrow) in mouse lung tissue lysates (35ug/lane) u...
Background publications Wakabayashi, Matsumine, Nakazora, Hasegawa, Iino, Ota, Sonoda, Sudo, Uchida: "Fibulin-3 negatively regulates chondrocyte differentiation." in: Biochemical and biophysical research communications, Vol. 391, Issue 1, pp. 1116-21, 2010 (PubMed).

Okada, Kamatani, Takahashi, Matsuda, Hosono, Ohmiya, Daigo, Yamamoto, Kubo, Nakamura, Kamatani: "A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci." in: Human molecular genetics, Vol. 19, Issue 11, pp. 2303-12, 2010 (PubMed).