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GBRR3 (AA 42-71), (N-Term) antibody

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N-Term, AA 42-71
(9), (7), (1)
(1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(9), (7)
Pubmed 4 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of Human GBRR3
Isotype Ig
Specificity This antibody recognizes Human GBRR3 (N-term).
Purification Protein A column, followed by peptide affinity purification
Background GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel (By similarity).Synonyms: GABRR3, Gamma-aminobutyric acid receptor subunit rho-3
Molecular Weight 54272 Da
Gene ID 200959
NCBI Accession NP_001099050
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-GBRR3 (AA 42-71), (N-Term) antibody (ABIN952470) Western blot analysis of GBRR3 Antibody (N-term) in NCI-H460 cell line lysates (35ug/...
Background publications Gratacòs, Costas, de Cid et al.: "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 6, pp. 808-16, 2009 (PubMed).

Craddock, Jones, Jones et al.: "Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype." in: Molecular psychiatry, Vol. 15, Issue 2, pp. 146-53, 2010 (PubMed).

Muzny, Scherer, Kaul et al.: "The DNA sequence, annotation and analysis of human chromosome 3. ..." in: Nature, Vol. 440, Issue 7088, pp. 1194-8, 2006 (PubMed).

Croci, Brändstatter, Enz: "ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2." in: The Journal of biological chemistry, Vol. 278, Issue 8, pp. 6128-35, 2003 (PubMed).

Catalog No. ABIN952470
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