HOXB8 antibody (C-Term)

Catalog No. ABIN952779

This anti-HOXB8 antibody is a Rabbit Polyclonal antibody detecting HOXB8 in WB and EIA. Suitable for Human.

Quick Overview for HOXB8 antibody (C-Term) (ABIN952779)

Target: HOXB8 (Homeobox B8 (HOXB8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-HOXB8 Antibody

Binding Specificity: AA 214-243, C-Term

Specificity: This antibody recognizes Human HOXB8 / HOX2D (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 214-243 amino acids from the C-terminal region of human HOXB8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HOXB8

Target: HOXB8 (Homeobox B8 (HOXB8))

Alternative Name: HOXB8 / HOX2D

Background: This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.Synonyms: Homeobox protein Hox-B8, Hox-2.4, Hox-2D

Molecular Weight: 27574 Da

Gene ID: 3218

NCBI Accession: NP_076921