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INSC antibody (Middle Region)

This anti-INSC antibody is a Rabbit Polyclonal antibody detecting INSC in WB and IHC (p). Suitable for Human.
Catalog No. ABIN952908

Quick Overview for INSC antibody (Middle Region) (ABIN952908)

Target

See all INSC Antibodies
INSC (Inscuteable Homolog (INSC))

Reactivity

  • 44
  • 19
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 44
Rabbit

Clonality

  • 44
Polyclonal

Conjugate

  • 13
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This INSC antibody is un-conjugated

Application

  • 21
  • 20
  • 17
  • 13
  • 13
  • 7
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

    • 15
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 416-446, Middle Region

    Specificity

    This antibody recognizes Human INSC (Center).

    Purification

    Protein A column, followed by peptide affinity purification

    Immunogen

    KLH conjugated synthetic peptide between 416~446 amino acids from the Central region of Human INSC

    Isotype

    Ig Fraction
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    INSC (Inscuteable Homolog (INSC))

    Alternative Name

    INSC

    Background

    In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).Synonyms: Protein inscuteable homolog

    Molecular Weight

    63469 Da

    Gene ID

    387755

    NCBI Accession

    NP_001027024
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