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Details for Product No. ABIN952931

Integrator Complex Subunit 1 (INTS1) (N-Term) antibody

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Antigen
Synonyms INT1, NET28, 1110015K06Rik, fa14a05, wu:fa14a05, wu:fa55a06, DDBDRAFT_0218704, DDBDRAFT_0234073, DDB_0218704, DDB_0234073, INTS1
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN952931
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide selected from the N-terminal region of Human INTS1
Specificity This antibody recognizes Human INTS1 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name INTS1
Background INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).
Alternate names: Int1, Integrator complex subunit 1, KIAA1440
Molecular Weight 244297 Da
Gene ID 26173
NCBI Accession NP_001073922
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Baillat, Hakimi, Näär et al.: "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II." in: Cell, Vol. 123, Issue 2, pp. 265-76, 2005 (PubMed).

Nusbaum, Mikkelsen, Zody et al.: "DNA sequence and analysis of human chromosome 8." in: Nature, Vol. 439, Issue 7074, pp. 331-5, 2006 (PubMed).

Alternatives for antigen "Integrator Complex Subunit 1 (INTS1)", type "Antibodies"
Hosts (8)
Reactivities (8), (1)
Applications (7), (2), (1)
Epitopes (5), (2), (1)
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