LALBA antibody (Lactalbumin, alpha-) (AA 37-68)

Details for Product anti-LALBA Antibody No. ABIN953131, Supplier: Log in to see
Antigen
  • LALBA
  • AW208827
  • a-LACTA
  • alfaLA
  • lactalbumin, alpha-
  • lactalbumin, alpha
  • LALBA
  • Lalba
Epitope
AA 37-68, Middle Region
10
9
7
6
5
5
5
4
3
2
2
2
1
Reactivity
Human
100
9
8
6
1
1
1
1
1
1
Host
Rabbit
87
26
4
Clonality
Polyclonal
Conjugate
This LALBA antibody is un-conjugated
8
8
6
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
71
59
32
28
25
13
13
7
6
6
5
4
3
2
2
2
1
Options
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Immunogen Synthetic peptide - KLH conjugated - corresponding to the central region (between 37-68aa) of human LALBA.
Isotype Ig
Specificity This antibody recognizes LALBA.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified through a protein A column followed by peptide affinity purification
Alternative Name LALBA (LALBA Antibody Abstract)
Background The LALBA gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells.Synonyms: Alpha-lactalbumin, LALBA, LYZL7, Lactose synthase B protein, Lysozyme-like protein 7
Gene ID 3906
NCBI Accession NP_002280
Research Area Metabolism
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Lactalbumin, alpha- (LALBA) (AA 37-68), (Middle Region) antibody (ABIN953131) Western blot analysis in CEM cell line lysates (35ug/lane) using LALBA  Antibody . Th...
Background publications Tolin, De Franceschi, Spolaore, Frare, Canton, Polverino de Laureto, Fontana: "The oleic acid complexes of proteolytic fragments of alpha-lactalbumin display apoptotic activity." in: The FEBS journal, Vol. 277, Issue 1, pp. 163-73, 2010 (PubMed).

Rösner, Redfield: "The human alpha-lactalbumin molten globule: comparison of structural preferences at pH 2 and pH 7." in: Journal of molecular biology, Vol. 394, Issue 2, pp. 351-62, 2009 (PubMed).

Wang, Yang, Tang, Sun, Zhang, Guo, Gong, Liu, Li, Zhang, Dai, Li: "Expression and characterization of bioactive recombinant human alpha-lactalbumin in the milk of transgenic cloned cows." in: Journal of dairy science, Vol. 91, Issue 12, pp. 4466-76, 2008 (PubMed).

Ramboarina, Redfield: "Probing the effect of temperature on the backbone dynamics of the human alpha-lactalbumin molten globule." in: Journal of the American Chemical Society, Vol. 130, Issue 46, pp. 15318-26, 2008 (PubMed).

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