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MEX3B antibody (Mex-3 Homolog B (C. Elegans)) (N-Term)

Details for Product anti-MEX3B Antibody No. ABIN953401, Supplier: Log in to see
Antigen
  • 4931439A04Rik
  • fam54b
  • M-04814
  • mex-3b
  • MEX-3B
  • mKIAA2009
  • Rkhd3
  • rkhd3
  • RKHD3
  • RNF195
  • wu:fc13g02
  • wu:fj58h02
  • zgc:158350
Epitope
N-Term, AA 36-65
17
15
2
2
1
1
1
1
1
Reactivity
Human
27
4
4
Host
Rabbit
25
2
Clonality
Polyclonal
Conjugate
This MEX3B antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
24
19
2
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human MEX3B
Isotype Ig
Specificity This antibody reacts to MEX3B.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name MEX3B / RKHD3 (MEX3B Antibody Abstract)
Background RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms.Synonyms: KIAA2009, RING finger and KH domain-containing protein 3, RING finger protein 195, RNA-binding protein MEX3B, RNF195
Molecular Weight 58832 Da
Gene ID 84206
NCBI Accession NP_115622
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-MEX3B antibody (Mex-3 Homolog B (C. Elegans)) (N-Term) (ABIN953401) MEX3B Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35µg/lan...
Background publications Nicolas, Poitelon, Chouery, Salem, Levy, Mégarbané, Delague: "CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592." in: European journal of human genetics : EJHG, Vol. 18, Issue 10, pp. 1107-13, 2010 (PubMed).

Courchet, Buchet-Poyau, Potemski, Brès, Jariel-Encontre, Billaud: "Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules." in: The Journal of biological chemistry, Vol. 283, Issue 46, pp. 32131-42, 2008 (PubMed).

Willer, Speliotes, Loos, Li, Lindgren, Heid, Berndt, Elliott, Jackson, Lamina, Lettre, Lim, Lyon, McCarroll, Papadakis, Qi, Randall, Roccasecca, Sanna, Scheet, Weedon, Wheeler, Zhao, Jacobs, Prokopenko, Soranzo, Tanaka, Timpson, Almgren, Bennett, Bergman,: "Six new loci associated with body mass index highlight a neuronal influence on body weight regulation." in: Nature genetics, Vol. 41, Issue 1, pp. 25-34, 2008 (PubMed).

Buchet-Poyau, Courchet, Le Hir, Séraphin, Scoazec, Duret, Domon-Dell, Freund, Billaud: "Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies." in: Nucleic acids research, Vol. 35, Issue 4, pp. 1289-300, 2007 (PubMed).

Barrios-Rodiles, Brown, Ozdamar, Bose, Liu, Donovan, Shinjo, Liu, Dembowy, Taylor, Luga, Przulj, Robinson, Suzuki, Hayashizaki, Jurisica, Wrana: "High-throughput mapping of a dynamic signaling network in mammalian cells." in: Science (New York, N.Y.), Vol. 307, Issue 5715, pp. 1621-5, 2005 (PubMed).