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MNDA antibody (N-Term)

MNDA Reactivity: Human WB, FACS, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN953470
  • Target See all MNDA Antibodies
    MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-61, N-Term
    Reactivity
    • 37
    • 3
    • 1
    Human
    Host
    • 34
    • 4
    Rabbit
    Clonality
    • 36
    • 2
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MNDA antibody is un-conjugated
    Application
    • 26
    • 23
    • 22
    • 13
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human MNDA (N-term).
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human MNDA
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MNDA Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
    Alternative Name
    MNDA (MNDA Products)
    Synonyms
    PYHIN3 antibody, A730048F03 antibody, Ifi205b antibody, myeloid cell nuclear differentiation antigen antibody, interferon activated gene 211 antibody, MNDA antibody, Ifi211 antibody
    Background
    The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.Synonyms: Myeloid cell nuclear differentiation antigen
    Molecular Weight
    45836 Da
    Gene ID
    4332
    NCBI Accession
    NP_002423
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