Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) (N-Term), (AA 23-53) antibody

Details for Product No. ABIN953658
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Antigen
Synonyms Neb2, PPP1R6, PPP1R9, SPINO, Spn, SPL
Epitope
N-Term, AA 23-53
(8), (7), (3), (2), (2), (1), (1)
Reactivity
Human
(27), (17), (15), (12), (12)
Host
Rabbit
(27), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(20), (10), (9), (3), (2)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN953658
357.50 $
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Immunogen KLH conjugated synthetic peptide between 23-53 amino acids from the N-terminal region of Human Neurabin-2. Genename: PPP1R9B
Specificity This antibody recognizes Human Neurabin-2 (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name Neurabin-2
Background Spinophilin is a regulatory subunit of protein phosphatase-1 catalytic subunit (PP1, see MIM 176875) and is highly enriched in dendritic spines, specialized protrusions from dendritic shafts that receive most of the excitatory input in the central nervous system (Allen et al., 1997 [PubMed 9275233]).
Alternate names: Neurabin-II, PPP1R6, PPP1R9B, Protein phosphatase 1 regulatory subunit 9B, Spinophilin
Molecular Weight 89192 Da
Gene ID 84687
NCBI Accession NP_115984
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Meng, Kanwar, Du et al.: "PPP1R9B (Neurabin 2): involvement and dynamics in the NK immunological synapse." in: European journal of immunology, Vol. 39, Issue 2, pp. 552-60, 2009 (PubMed).

Sagara, Kawasaki, Iemura et al.: "Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration." in: Oncogene, Vol. 28, Issue 10, pp. 1357-65, 2009 (PubMed).

Martins-de-Souza, Gattaz, Schmitt et al.: "Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia." in: European archives of psychiatry and clinical neuroscience, Vol. 259, Issue 3, pp. 151-63, 2009 (PubMed).

Rajagopal, Ji, Xu et al.: "Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1)." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 18060-71, 2010 (PubMed).

Pinheiro, Bulik, Thornton et al.: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

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