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Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 1 (RPS6KC1) (AA 19-47), (N-Term) antibody

Details for Product No. ABIN954626, Supplier: Log in to see
Antigen
  • MGC81290
  • RPS6KC1
  • AA682037
  • B130003F20Rik
  • C80612
  • Rpk118
  • RPK118
  • humS6PKh1
Epitope
AA 19-47, N-Term
17
15
3
2
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
25
18
2
Host
Rabbit
31
4
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
32
26
17
9
4
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of Human RPS6KC1. Genename: RPS6KC1
Isotype Ig
Specificity Recognizes RPS6KC1 (N-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name RPS6KC1 / RPK118 (RPS6KC1 Antibody Abstract)
Background RPS6KC1 shows homology to the S6 kinase family of serine/threonine kinases. It is a sphingosine kinase-1 (SPHK1)-binding protein that may be involved in transmitting sphingosine 1 phosphate (SPP)-mediated signaling into the cell. Cellular localization: Cytoplasm. Membrane. Also found in some small dot-like or ring-shaped early endosome structures.Synonyms: 52 kDa ribosomal protein S6 kinase, Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein, Ribosomal protein S6 kinase delta-1, S6K-delta-1, SPHK1-binding protein
Gene ID 26750
NCBI Accession NP_001129610
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 1 (RPS6KC1) (AA 19-47), (N-Term) antibody (ABIN954626) Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human skeletal mus...
Western Blotting (WB) image for anti-Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 1 (RPS6KC1) (AA 19-47), (N-Term) antibody (ABIN954626) Western blot analysis in Mouse liver tissue lysates (35ug/lane) using RPS6KC1 Antibod...
Background publications Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Liu, Yang, Yuan et al.: "RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains." in: Molecules and cells, Vol. 19, Issue 1, pp. 39-45, 2005 (PubMed).

Lehner, Semple, Brown et al.: "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region." in: Genomics, Vol. 83, Issue 1, pp. 153-67, 2003 (PubMed).

Hayashi, Okada, Igarashi et al.: "Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein." in: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 33319-24, 2002 (PubMed).