You are viewing an incomplete version of our website. Please click to reload the website as full version.

Septin 2 (SEPT2) (AA 279-309), (C-Term) antibody

Details for Product No. ABIN954726, Supplier: Log in to see
Antigen
  • SEPT2
  • sept2
  • Septin-2B
  • diff6
  • hnedd5
  • nedd5
  • pnutl3
  • sept2-B
  • Septin-2
  • DIFF6
  • NEDD5
  • Pnutl3
  • hNedd5
  • AW208991
  • Nedd-5
  • Nedd5
  • mKIAA0158
  • Vesp11
  • wu:fb52g01
  • wu:fb99a01
  • Septin-2A
  • Septin-A
  • septa
  • xlsepta
  • Sep-02
  • septin 2-like
  • septin 2
  • septin-2A
  • ANL34
  • Septin-2
  • LOC416777
  • SEPT2
  • sept2-a
  • sepT2
  • sept2
  • Sept2
  • sept2-b
Epitope
C-Term, AA 279-309
24
14
14
4
4
3
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
109
55
51
10
3
3
3
3
2
2
2
2
2
1
1
Host
Rabbit
75
24
10
Clonality
Polyclonal
Conjugate
Un-conjugated
5
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
92
54
20
13
13
11
5
2
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of Human SEPT2 Genename: SEPT2
Isotype Ig
Specificity Recognizes SEPT2 (C-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name Septin-2 (SEPT2 Antibody Abstract)
Background Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.Synonyms: DIFF6, KIAA0158, NEDD-5, NEDD5, Neural precursor cell expressed developmentally down-regulated protein 5, SEPT-2, SEPT2, Septin2
Gene ID 4735
NCBI Accession NP_001008491
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Septin 2 (SEPT2) (AA 279-309), (C-Term) antibody (ABIN954726) Western blot analysis of AP53852PU-N SEPT2 Antibody (C-term) Cat.-No AP53852PU-N in N...
Background publications Guey, García-Closas, Murta-Nascimento, Lloreta, Palencia, Kogevinas, Rothman, Vellalta, Calle, Marenne, Tardón, Carrato, García-Closas, Serra, Silverman, Chanock, Real, Malats: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, 2010 (PubMed).

Hosgood, Menashe, He, Chanock, Lan: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, 2009 (PubMed).

Shen, Vermeulen, Rajaraman, Menashe, He, Chapman, Yeager, Thomas, Burdett, Hutchinson, Yuenger, Chanock, Lan: "Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China." in: Environmental and molecular mutagenesis, Vol. 50, Issue 4, pp. 285-90, 2009 (PubMed).

Mostowy, Danckaert, Tham, Machu, Guadagnini, Pizarro-Cerdá, Cossart: "Septin 11 restricts InlB-mediated invasion by Listeria." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11613-21, 2009 (PubMed).