SIM1 antibody (N-Term)

Catalog No. ABIN954809

Product Details anti-SIM1 Antibody

Target: SIM1 (Single-Minded Homolog 1 (SIM1))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recongnizes Human SIM1 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human SIM1 Genename: SIMI1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SIM1

Target: SIM1 (Single-Minded Homolog 1 (SIM1))

Alternative Name: SIM1 (SIM1 Products)

Synonyms: bHLHe14 antibody, mSIM1 antibody, single-minded family bHLH transcription factor 1 antibody, single-minded homolog 1 (Drosophila) antibody, single-minded family bHLH transcription factor 1a antibody, SIM1 antibody, Sim1 antibody, sim1a antibody

Background: SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.Synonyms: BHLHE14, Class E basic helix-loop-helix protein 14, Single-minded homolog 1

Molecular Weight: 85515 Da

Gene ID: 6492

NCBI Accession: NP_005059