SIT1 antibody (C-Term)
This anti-SIT1 antibody is a Rabbit Polyclonal antibody detecting SIT1 in WB and EIA. Suitable for Human.
Quick Overview for SIT1 antibody (C-Term) (ABIN954810)
Target
See all SIT1 Antibodies
SIT1
(Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1))
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
This SIT1 antibody is un-conjugated
Application
Western Blotting (WB), Enzyme Immunoassay (EIA)
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Binding Specificity
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AA 160-189, C-Term
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Specificity
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This antibody recognizes Human SIT1 / SIT (C-term).
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Purification
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Affinity Chromatography on Protein A
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Immunogen
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KLH conjugated synthetic peptide between 160-189 amino acids from the C-terminal region of Human SIT1 Genename: SIT1
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Isotype
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Ig Fraction
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Application Notes
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Optimal working dilution should be determined by the investigator.
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Restrictions
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For Research Use only
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Format
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Liquid
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Concentration
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0.25 mg/mL
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Buffer
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PBS, 0.09 % Sodium Azide
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Preservative
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Sodium azide
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Precaution of Use
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This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
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Avoid repeated freezing and thawing.
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Storage
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4 °C/-20 °C
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Storage Comment
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Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Target
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SIT1
(Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1))
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Alternative Name
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SIT1 / SIT
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Background
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Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.Synonyms: SHP2-interacting transmembrane adapter protein, Signaling threshold-regulating transmembrane adapter 1, Suppression-inducing transmembrane adapter 1
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Molecular Weight
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21126 Da
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Gene ID
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27240
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NCBI Accession
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NP_055265
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