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Taste Receptor, Type 2, Member 44 (TAS2R31) (AA 279-309), (C-Term) antibody

Details for Product No. ABIN955084, Supplier: Login to see
Antigen
  • TAS2R44
  • T2R31
  • T2R44
  • T2R53
Epitope
C-Term, AA 279-309
17
15
2
Reactivity
Human
21
Host
Rabbit
21
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
19
14
2
Supplier
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Immunogen KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of human TAS2R31
Isotype Ig
Specificity This antibody reacts to TAS2R31.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name TAS2R44 (TAS2R31 Antibody Abstract)
Background TAS2R44 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.Synonyms: T2R53, Taste receptor T2R44, Taste receptor type 2 member 44
Molecular Weight 35296 Da
Gene ID 259290
NCBI Accession NP_795366
Research Area Neurology
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Taste Receptor, Type 2, Member 44 (TAS2R31) (AA 279-309), (C-Term) antibody (ABIN955084) TAS2R31 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35µg/...
Background publications Pronin, Xu, Tang et al.: "Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin." in: Current biology : CB, Vol. 17, Issue 16, pp. 1403-8, 2007 (PubMed).

Kuhn, Bufe, Winnig et al.: "Bitter taste receptors for saccharin and acesulfame K." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 45, pp. 10260-5, 2004 (PubMed).

Fischer, Gilad, Man et al.: "Evolution of bitter taste receptors in humans and apes." in: Molecular biology and evolution, Vol. 22, Issue 3, pp. 432-6, 2005 (PubMed).

Pronin, Tang, Connor et al.: "Identification of ligands for two human bitter T2R receptors." in: Chemical senses, Vol. 29, Issue 7, pp. 583-93, 2004 (PubMed).

Zhang, Hoon, Chandrashekar et al.: "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways." in: Cell, Vol. 112, Issue 3, pp. 293-301, 2003 (PubMed).