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Taste Receptor, Type 2, Member 7 (TAS2R7) (AA 207-235), (C-Term) antibody

Details for Product No. ABIN955085, Supplier: Log in to see
Antigen
  • t2r1
  • t2r7
  • trb4
  • T2R7
  • Tas2r13
  • Tas2r7
  • STC74
  • T2R30
  • Tas2r30
  • mt2r42
  • TRB4
  • Patr-T2R7
Epitope
C-Term, AA 207-235
17
15
3
2
1
1
1
1
1
1
Reactivity
Human
44
2
2
Host
Rabbit
46
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
33
22
12
6
3
3
Supplier
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Immunogen KLH conjugated synthetic peptide between 207-235 amino acids from the C-terminal region of human TAS2R7
Isotype Ig
Specificity This antibody reacts to TAS2R7.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name TAS2R7 (TAS2R7 Antibody Abstract)
Background This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.Synonyms: TRB4, Taste receptor family B member 4, Taste receptor type 2 member 7
Molecular Weight 36550 Da
Gene ID 50837
NCBI Accession NP_076408
Research Area Neurology
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Taste Receptor, Type 2, Member 7 (TAS2R7) (AA 207-235), (C-Term) antibody (ABIN955085) TAS2R7 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35µg/lane)...
Background publications Go, Satta, Takenaka et al.: "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates." in: Genetics, Vol. 170, Issue 1, pp. 313-26, 2005 (PubMed).

Fischer, Gilad, Man et al.: "Evolution of bitter taste receptors in humans and apes." in: Molecular biology and evolution, Vol. 22, Issue 3, pp. 432-6, 2005 (PubMed).

Zhang, Hoon, Chandrashekar et al.: "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways." in: Cell, Vol. 112, Issue 3, pp. 293-301, 2003 (PubMed).

Montmayeur, Matsunami: "Receptors for bitter and sweet taste." in: Current opinion in neurobiology, Vol. 12, Issue 4, pp. 366-71, 2002 (PubMed).

Margolskee: "Molecular mechanisms of bitter and sweet taste transduction." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 1-4, 2002 (PubMed).