Transcription Factor A, Mitochondrial (TFAM) (C-Term), (AA 223-254) antibody

Details for Product No. ABIN955168
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Antigen
Synonyms Hmgts, mtTFA, tsHMG, AI661103, Mttfa, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3, tcf6, mttf1, mttfa, tcf6l1, tcf6l2, tcf6l3, mttfa-A, xl-mtTFA, MGC153358, zgc:153358
Epitope
C-Term, AA 223-254
(6), (6), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(51), (24), (22), (14), (13), (13)
Host
Rabbit
(64), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Flow Cytometry (FACS)
(45), (25), (21), (20), (17), (16), (10), (3), (3), (3), (3), (2)
Pubmed 2 references available
Catalog no. ABIN955168
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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Immunogen KLH conjugated synthetic peptide between 223-254 amino acids from the C-terminal region of human TFAM
Specificity This antibody detects TFAM (C-term).
Purification Protein A column followed by peptide affinity purification
Alternative Name TFAM / TCF6
Background This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Alternate names: Mitochondrial transcription factor 1, MtTF1, TCF-6, TCF6L2, Transcription factor 6, Transcription factor 6-like 2, mitochondrial Transcription factor A
Gene ID 7019
NCBI Accession NP_003192
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Akhmetov, Popov, Missina et al.: "[Association of the mitochondrial transcription factor (TFAM) gene polymorphism with physical performance of athletes]." in: Fiziologiia cheloveka, Vol. 36, Issue 2, pp. 121-5, 2010 (PubMed).

Corneveaux, Myers, Allen et al.: "Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals." in: Human molecular genetics, Vol. 19, Issue 16, pp. 3295-301, 2010 (PubMed).

Hosts (64), (3)
Reactivities (51), (24), (22), (14), (13), (13)
Applications (45), (25), (21), (20), (17), (16), (10), (3), (3), (3), (3), (2)
Conjugates (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (6), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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