F13A1 antibody

Catalog No. ABIN957859

Product Details anti-F13A1 Antibody

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F13A1 antibody is un-conjugated

Application: Immunoelectrophoresis (IEP), Immunodiffusion (ID)

Specificity: Human F13A1 / Factor XIIIa. The defined antibody reactivity is restricted to Factor XIII and FXIIIa in plasma and to platelet FXIII. As tested at the level of sensitivity of immunoprecipitation techniques a single precipitin line is obtained in bidimensional electrophoresis, immunoelectrophoresis and double radial immunodiffusion (Ouchterlony) which shows a reaction of full identity with A subunits of FXIII. No reaction is obtained with FXIII-depleted plasma and with B subunits. Cross-reactivity The antiserum does not cross-react with any other human plasma proteins as tested in gel-diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail.

Purification: Immunoaffinity absorbed

Immunogen: Human Factor XIII-A

Type of Immunogen: Purified protein

Application Details

Application Notes: Approved: ID, IE

Usage: This product is intended for use in precipitating techniques as electroimmunodiffusion, immunoelectrophoresis and single and double radial immunodiffusion (Mancini, Ouchterlony). To prepare an adsorbent for immunoaffinity purification of FXIII. If used in more sensitive test procedures or as catching or detection antibody in solid phase immunoassays specificity controls should always be include. Increase in plasma FXIII has been observed in type IV hyperlipoproteinaemia and in combined hyperlipodaemia. Congenital and acquired FXIII deficiencies have also been reported. In some cases of myeloma, inhibition of FXIII activity by the paraproteins may occur.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile distilled water 1 ml

Concentration: Lot specific

Buffer: Lyophilized antiserum

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C
Short term: +4°C. Avoid repeat freeze-thaw cycles.

Target Details for F13A1

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Alternative Name: F13A1 / Factor XIIIa (F13A1 Products)

Synonyms: F13a antibody, f13a1 antibody, wu:fo83d04 antibody, zgc:153334 antibody, F13A1 antibody, F13A antibody, 1200014I03Rik antibody, AI462306 antibody, coagulation factor XIII A1 chain antibody, coagulation factor XIII, A1 polypeptide b antibody, coagulation factor XIII A chain antibody, coagulation factor XIII, A1 subunit antibody, F13a1 antibody, f13a1b antibody, F13A1 antibody

Background: Name/Gene ID: F13A1

Synonyms: F13A1, Coagulation factor XIIIa, Factor XIIIa, Fibrinoligase, FSF, A subunit, Transglutaminase. plasma, Transglutaminase A chain, F13A, TGASE

Gene ID: 2162

UniProt: P00488