ASK1 antibody
Quick Overview for ASK1 antibody (ABIN965600)
Target
See all ASK1 (MAP3K5) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- ASK1 (Ab-83) antibody detects endogenous levels of ASK1 protein around serine 83.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human ASK1 around the phosphorylation site of serine 83 (G-S-SP-V-G).
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Application Notes
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WB: 1:500~1:1000
IHC: 1:50~1:100. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100ug/100ul.
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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: "AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23432-40, (2003) (PubMed).
: "Estrogen inhibits paclitaxel-induced apoptosis via the phosphorylation of apoptosis signal-regulating kinase 1 in human ovarian cancer cell lines." in: Endocrinology, Vol. 145, Issue 1, pp. 49-58, (2003) (PubMed).
: "Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1." in: Molecular and cellular biology, Vol. 21, Issue 3, pp. 893-901, (2001) (PubMed).
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- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
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Alternative Name
- ASK1
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Pathways
- MAPK Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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