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Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) antibody

Antigen

Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
Synonyms ASK1, MEKK5, MAPKKK5, MAP3K5, Ask1, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
3 references available
Catalog no. ABIN965600
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Alternative name ASK1
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human ASK1 around the phosphorylation site of serine 83 (G-S-SP-V-G).
Specificity ASK1 (Ab-83) antibody detects endogenous levels of ASK1 protein around serine 83.

Application Details
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Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Kim, Khursigara, Sun et al.: "Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1." in: Molecular and cellular biology, Vol. 21, Issue 3, pp. 893-901, 2001 (PubMed).

Yuan, Feldman, Sussman et al.: "AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23432-40, 2003 (PubMed).

Mabuchi, Ohmichi, Kimura et al.: "Estrogen inhibits paclitaxel-induced apoptosis via the phosphorylation of apoptosis signal-regulating kinase 1 in human ovarian cancer cell lines." in: Endocrinology, Vol. 145, Issue 1, pp. 49-58, 2003 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)", type "Antibodies"
Hosts Rabbit (166), Mouse (5)
Reactivities Human (169), Mouse (Murine) (67), Rat (Rattus) (43), Dog (Canine) (15), Horse (Equine) (15), Chicken (10), Cow (Bovine) (5)
Applications Western Blotting (WB) (104), ELISA (69), Immunofluorescence (IF) (59), Immunohistochemistry (IHC) (49), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (37), Immunocytochemistry (ICC) (14), Immunoprecipitation (IP) (5), Flow Cytometry (FACS) (4), Dot Blot (Dot) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Immunohistochemistry (Fixed) (IHC (fx)) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (6), Alexa Fluor 488 (6), Alexa Fluor 555 (6), Alexa Fluor 647 (6), PE,Cy5.5 (6), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pSer83 (22), pSer966 (17), C-Term (9), pSer1033 (6), N-Term (5), Ser83 (4), Ser966 (4), pSer967 (4), pThr845 (4), Ser1033 (2), Thr842 (2), AA 1198-1216 (1), AA 1276-1291 (1), AA 280 (1), AA 76-87,pSer83 (1), Internal Region (1), pSer192 (1), pSer260 (1), pSer428 (1), pThr668 (1)