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MAP3K5 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 5)

Details for Product anti-MAP3K5 Antibody No. ABIN965600, Supplier: Login to see New
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Synonyms 7420452D20Rik, ASK, ASK1, MAPKKK5, Mekk5, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11, MEKK5, MAP3K5
(371), (138), (78), (4), (1)
(357), (22)
This MAP3K5 antibody is un-conjugated
(12), (12), (11), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5)
Immunohistochemistry (IHC)
(291), (146), (127), (57), (56), (39), (23), (11), (7), (6), (6), (2), (1), (1), (1)
Pubmed 3 references available
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Quantity 100 μg
Shipping to United States ( )
Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human ASK1 around the phosphorylation site of serine 83 (G-S-SP-V-G).
Specificity ASK1 (Ab-83) antibody detects endogenous levels of ASK1 protein around serine 83.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name ASK1 (MAP3K5 Antibody Abstract)
Pathways MAPK Signaling
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Mabuchi, Ohmichi, Kimura et al.: "Estrogen inhibits paclitaxel-induced apoptosis via the phosphorylation of apoptosis signal-regulating kinase 1 in human ovarian cancer cell lines." in: Endocrinology, Vol. 145, Issue 1, pp. 49-58, 2003 (PubMed).

Yuan, Feldman, Sussman et al.: "AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23432-40, 2003 (PubMed).

Kim, Khursigara, Sun et al.: "Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1." in: Molecular and cellular biology, Vol. 21, Issue 3, pp. 893-901, 2001 (PubMed).

Catalog No. ABIN965600
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