Activating Transcription Factor 2 (ATF2) antibody

Details for Product No. ABIN965613
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Antigen
Synonyms CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420, CRE-BP1, CREB2, HB16, TREB7, Atf-2, CRE-BP, Creb2, D130078H02Rik, D18875, Tg(Gzma-Klra1)7Wum, mXBP, atf2-A, atf2l, ATF1, ATF2, HFB1-GDNF, HSCR3
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(534), (362), (346), (111), (89), (72), (62), (12), (2), (2), (1), (1), (1)
Host
Rabbit
(498), (23), (8), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(18), (18), (18), (16), (16), (16), (16), (16), (16), (16), (16), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(324), (188), (160), (144), (110), (96), (56), (16), (12), (11), (6), (3), (3), (2), (1), (1)
Pubmed 5 references available
Quantity 100 μg
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Catalog No. ABIN965613
385.00 $
Plus shipping costs $45.00

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  • +1 404 474 4654
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 71 or 53 (T-P-TP-P-T).
Specificity ATF-2(Ab-71or 53) antibody detects endogenous levels of total ATF-2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name ATF2
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Abdel-Hafiz, Heasley, Kyriakis et al.: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, 1993 (PubMed).

van Dam, Wilhelm, Herr et al.: "ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents." in: The EMBO journal, Vol. 14, Issue 8, pp. 1798-811, 1995 (PubMed).

Gupta, Campbell, Dérijard et al.: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, 1995 (PubMed).

Waetzig, Seegert, Rosenstiel et al.: "p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 10, pp. 5342-51, 2002 (PubMed).

Sevilla, Santos, Vega et al.: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, 2004 (PubMed).

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