beta Catenin antibody

Catalog No. ABIN965662

This Rabbit Polyclonal antibody specifically detects beta Catenin in IHC. It exhibits reactivity toward Human, Mouse and Rat and has been mentioned in 5+ publications.

Quick Overview for beta Catenin antibody (ABIN965662)

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Catenin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-beta Catenin Antibody

Specificity: -Catenin (Ab-33) antibody detects endogenous levels of total -Catenin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human Catenin around the phosphorylation site of serine 33 (L-D-SP-G-I).

Application Details

Application Notes: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-beta Catenin antibody (ABIN965662)

Okamura, Garcia-Rodriguez, Martinson, Qin, Virshup, Rao: "A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1." in: Molecular and cellular biology, Vol. 24, Issue 10, pp. 4184-95, (2004) (PubMed).

Marin, Bustos, Cesaro, Meggio, Pagano, Antonelli, Allende, Pinna, Allende: "A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 18, pp. 10193-200, (2003) (PubMed).

Xing, Clements, Kimelman, Xu: "Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex." in: Genes & development, Vol. 17, Issue 22, pp. 2753-64, (2003) (PubMed).

Barth, Stewart, Nelson: "T cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant beta-catenin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 9, pp. 4947-52, (1999) (PubMed).

Novak, Hsu, Leung-Hagesteijn, Radeva, Papkoff, Montesano, Roskelley, Grosschedl, Dedhar: "Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 8, pp. 4374-9, (1998) (PubMed).

Target Details for beta Catenin

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Alternative Name: Beta-Catenin

Pathways: Peptide Hormone Metabolism