beta Catenin antibody (C-Term)

Catalog No. ABIN6254224

This Goat Polyclonal antibody specifically detects beta Catenin in WB, IF, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse, Rat, Chicken, Cow, Dog, Pig, Rabbit, Sheep, Monkey, Hamster, Avian, Cat, Donkey, Goat, Guinea Pig and Horse.It has been mentioned in 1 publication

Quick Overview for beta Catenin antibody (C-Term) (ABIN6254224)

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Reactivity: Human, Mouse, Rat, Chicken, Cow, Dog, Pig, Rabbit, Sheep, Monkey, Hamster, Avian, Cat, Donkey, Goat, Guinea Pig, Horse

Host: Goat

Clonality: Polyclonal

Conjugate: This beta Catenin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-beta Catenin Antibody

Binding Specificity: C-Term

Purpose: Anti-beta-Catenin

Sequence: MDPMMEHEMG GHHPGADYPV DGLPDLGHAQ DLMDGLPPGD SNQLAWFDTD L

Specificity: Detects a band of approximately 95 kDa by Western blot in MNT1 and SH-SY5Y cell lysates.

Characteristics: Catenin (cadherin-associated protein), beta 1, 88 kDa

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 731 aa to the C-terminus of human beta Catenin produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000, IF:1:50-1:250, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Restrictions: For Research Use only

Handling

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

References for anti-beta Catenin antibody (ABIN6254224)

Balashova, Visina, Borodinsky: "Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation." in: Development (Cambridge, England), Vol. 144, Issue 8, pp. 1518-1530, (2017) (PubMed).

Target Details for beta Catenin

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Alternative Name: beta-Catenin

Background:

Goat polyclonal antibody to Catenin (cadherin-associated protein), beta 1. Beta Catenin is a 88 kDa protein and is a key downstream effector in the Wnt signalling pathway. It is involved in early embryonic development and tumorigenesis. Beta Catenin is part of a complex of proteins that constitute adherens junctions, necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. This protein anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.

cadherin-associated protein, CTNNB, CTNNB1, MRD19, armadillo antibody.

Molecular Weight: 88 kDa

Pathways: Peptide Hormone Metabolism