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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Jun Proto-Oncogene (JUN) antibody
|Synonyms||AP1, AP-1, c-Jun, fj36h07, zgc:65863, wu:fj36h07, jun|
Human, Mouse (Murine), Rat (Rattus)
Alternatives Immunohistochemistry (IHC)
|4 references available|
|Quantity||100ug (100ug/100ul) (Variants)|
|Price||385.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 5 to 7 Business Days|
|Immunogen||The antiserum was produced against synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of tyrosine 170 (P-V-YP-A-N).|
|Specificity||C-Jun (Ab-170) antibody detects endogenous levels of c-Jun protein around tyrosine 170.|
|Purification||The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.|
|Buffer||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol|
|Preservative||0.02% Sodium Azide|
|Storage||Store at -20°C/1 year.|
|Restrictions||For Research Use only|
Smeal, Binetruy, Mercola et al.: "Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73." in: Nature, Vol. 354, Issue 6353, pp. 494-6, 1992 (PubMed).
Dérijard, Hibi, Wu et al.: "JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain." in: Cell, Vol. 76, Issue 6, pp. 1025-37, 1994 (PubMed).
Kyriakis, Banerjee, Nikolakaki et al.: "The stress-activated protein kinase subfamily of c-Jun kinases." in: Nature, Vol. 369, Issue 6476, pp. 156-60, 1994 (PubMed).
Barilá, Mangano, Gonfloni et al.: "A nuclear tyrosine phosphorylation circuit: c-Jun as an activator and substrate of c-Abl and JNK." in: The EMBO journal, Vol. 19, Issue 2, pp. 273-81, 2000 (PubMed).