CARD9 antibody (N-Term)

Catalog No. ABIN965748

The Rabbit Polyclonal anti-CARD9 antibody (ABIN965748) specifically detects CARD9 in IHC. The antibody is reactive with Human and Rat samples.

Quick Overview for CARD9 antibody (N-Term) (ABIN965748)

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD9 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CARD9 Antibody

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human CARD9(Caspase recruitment domain-containing protein 9)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CARD9

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Alternative Name: CARD9

Background: CARD9(Caspase recruitment domain-containing protein 9) is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Three alternatively spliced variants of this gene encoding distinct isoforms have been reported.

Pathways: Activation of Innate immune Response