CD8 antibody

Catalog No. ABIN965817

Product Details anti-CD8 Antibody

Target: CD8

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This CD8 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Specificity: Ni-NTA purified recombinant human CD8 expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Storage: -20 °C

References for anti-CD8 antibody (ABIN965817)

Veillette, Bookman, Horak, Bolen: "The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck." in: Cell, Vol. 55, Issue 2, pp. 301-8, (1988) (PubMed).

Target Details for CD8

Target: CD8

Alternative Name: CD8 (CD8 Products)

Synonyms: CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, CD8a molecule antibody, CD8A antibody

Background: CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.

Gene ID: 925