CDC25A antibody

Catalog No. ABIN965832

Cited in 2+ publications. The Rabbit Polyclonal anti-CDC25A antibody (ABIN965832) specifically detects CDC25A in IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CDC25A antibody (ABIN965832)

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC25A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CDC25A Antibody

Specificity: Cdc25A (Ab-75) antibody detects endogenous levels of total cdc25A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human cdc25A around the phosphorylation site of serine 75.

Application Details

Application Notes: WB: 1:500~1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-CDC25A antibody (ABIN965832)

Jin, Shirogane, Xu, Nalepa, Qin, Elledge, Harper: "SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase." in: Genes & development, Vol. 17, Issue 24, pp. 3062-74, (2003) (PubMed).

Shimuta, Nakajo, Uto, Hayano, Okazaki, Sagata: "Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition." in: The EMBO journal, Vol. 21, Issue 14, pp. 3694-703, (2002) (PubMed).

Target Details for CDC25A

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Alternative Name: cdc25A

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase