Cytokeratin 7 antibody

Catalog No. ABIN965903

The Mouse Monoclonal anti-Cytokeratin 7 antibody has been validated for WB, FACS and ELISA. It is suitable to detect Cytokeratin 7 in samples from Human. There are 3+ publications available.

Quick Overview for Cytokeratin 7 antibody (ABIN965903)

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Clone: 5D12

Product Details anti-Cytokeratin 7 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CK7 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-Cytokeratin 7 antibody (ABIN965903)

Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: "New consensus nomenclature for mammalian keratins." in: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).

Bouwens: "Cytokeratins and cell differentiation in the pancreas." in: The Journal of pathology, Vol. 184, Issue 3, pp. 234-9, (1998) (PubMed).

Rosenberg, Fuchs, Le Beau, Eddy, Shows: "Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12." in: Cytogenetics and cell genetics, Vol. 57, Issue 1, pp. 33-8, (1991) (PubMed).

Target Details for Cytokeratin 7

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Alternative Name: CK7

Background: CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants, however, not all variants have been fully described.
Synonyms: KRT7, cytokeratin 7

Molecular Weight: 51kDa

Gene ID: 3855