ELK1 antibody

Catalog No. ABIN966062

There are 4+ publications for this product available. The Rabbit Polyclonal anti-ELK1 antibody is suitable to detect ELK1 in samples from Human, Mouse and Rat. It has been validated for IHC.

Quick Overview for ELK1 antibody (ABIN966062)

Target: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELK1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-ELK1 Antibody

Specificity: Elk-1(Ab-389) Antibody detects endogenous levels of total Elk-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human Elk-1 around the phosphorylation site of serine 389 (P-R-SP-P-A).

Application Details

Application Notes: IHC: 1:50-1:100.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-ELK1 antibody (ABIN966062)

Cavigelli, Dolfi, Claret, Karin: "Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation." in: The EMBO journal, Vol. 14, Issue 23, pp. 5957-64, (1996) (PubMed).

Hill, Treisman: "Transcriptional regulation by extracellular signals: mechanisms and specificity." in: Cell, Vol. 80, Issue 2, pp. 199-211, (1995) (PubMed).

Janknecht, Ernst, Pingoud, Nordheim: "Activation of ternary complex factor Elk-1 by MAP kinases." in: The EMBO journal, Vol. 12, Issue 13, pp. 5097-104, (1994) (PubMed).

Marais, Wynne, Treisman: "The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain." in: Cell, Vol. 73, Issue 2, pp. 381-93, (1993) (PubMed).

Target Details for ELK1

Target: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Alternative Name: Elk-1

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling