Fibulin 5 antibody (C-Term)

Catalog No. ABIN966131

There are 2+ publications for this product available. The Rabbit Polyclonal anti-Fibulin 5 antibody is suitable to detect Fibulin 5 in samples from Human, Mouse and Rat. It has been validated for IHC.

Quick Overview for Fibulin 5 antibody (C-Term) (ABIN966131)

Target: Fibulin 5 (FBLN5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibulin 5 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Fibulin 5 Antibody

Binding Specificity: C-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human FBLN5 (Fibulin-5 precursor)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Fibulin 5 antibody (ABIN966131)

Stone, Braun, Russell, Kuehn, Lotery, Moore, Eastman, Casavant, Sheffield: "Missense variations in the fibulin 5 gene and age-related macular degeneration." in: The New England journal of medicine, Vol. 351, Issue 4, pp. 346-53, (2004) (PubMed).

Nakamura, Ruiz-Lozano, Lindner, Yabe, Taniwaki, Furukawa, Kobuke, Tashiro, Lu, Andon, Schaub, Matsumori, Sasayama, Chien, Honjo: "DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries." in: The Journal of biological chemistry, Vol. 274, Issue 32, pp. 22476-83, (1999) (PubMed).

Target Details for Fibulin 5

Target: Fibulin 5 (FBLN5)

Alternative Name: FBLN5

Background: FBLN5(Fibulin-5) promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling. FBLN5 (Fibulin-5) is expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes.

Pathways: SARS-CoV-2 Protein Interactome