FGF7 antibody (N-Term)

Catalog No. ABIN966138

Cited in 2+ publications. The Polyclonal anti-FGF7 antibody (ABIN966138) specifically detects FGF7 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for FGF7 antibody (N-Term) (ABIN966138)

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Reactivity: Human

Host: Please inquire

Clonality: Polyclonal

Conjugate: This FGF7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FGF7 Antibody

Binding Specificity: AA 51-65, N-Term

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human FGF7 (51-65aa), identical to the related mouse and rat sequence.

Application Details

Application Notes: WB: The detection limit for FGF7 is approximately 5ng/lane under non-reducing and reducing conditions.

Restrictions: For Research Use only

Handling

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Preservative: Thimerosal (Merthiolate), Sodium azide

Storage: -20 °C

References for anti-FGF7 antibody (ABIN966138)

Eberlé, Dubreuil, Mattei, Devilard, Lopez: "The human PRR2 gene, related to the human poliovirus receptor gene (PVR), is the true homolog of the murine MPH gene." in: Gene, Vol. 159, Issue 2, pp. 267-72, (1995) (PubMed).

Kelley, Pech, Seuanez, Rubin, OBrien, Aaronson: "Emergence of the keratinocyte growth factor multigene family during the great ape radiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 19, pp. 9287-91, (1992) (PubMed).

Target Details for FGF7

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Alternative Name: FGF7

Background: Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway