FYN Oncogene Related To SRC, FGR, YES (FYN) antibody

Details for Product No. ABIN966166
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Antigen
Synonyms fyn, c-fyn, zgc:86720, SLK, SYN, p59-FYN, AI448320, AW552119, PKC, cfyn-a, im:6908851, si:dkey-119m7.5, zgc:109996
Reactivity
Human
(142), (93), (59), (28), (27), (27), (25), (2)
Host
Mouse
(100), (49), (9)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA
(128), (70), (37), (24), (20), (17), (15), (10), (10), (6), (4), (3), (2), (2), (2), (1)
Pubmed 2 references available
Catalog no. ABIN966166
Quantity 0.1 mL
Price
467.50 $   Plus shipping costs $45.00
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Immunogen Purified recombinant fragment of human FYN expressed in E. Coli.
Clone 2A10
Isotype IgG1
Purification Ascitic fluid
Alternative Name FYN
Background This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Synonyms: SLK, SYN, MGC45350
Molecular Weight 61kDa
Gene ID 2534
Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Storage 4 °C
Product cited in: Lu, Zhu, Cvrljevic et al.: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, 2009 (PubMed).

Brignatz, Paronetto, Opi et al.: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, 2009 (PubMed).

Hosts (100), (49), (9)
Reactivities (142), (93), (59), (28), (27), (27), (25), (2)
Applications (128), (70), (37), (24), (20), (17), (15), (10), (10), (6), (4), (3), (2), (2), (2), (1)
Conjugates (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (30), (18), (9), (7), (6), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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