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FYN Oncogene Related To SRC, FGR, YES (FYN) antibody

Antigen

FYN Oncogene Related To SRC, FGR, YES (FYN)
Synonyms FYN, fyn, MGC52878, MGC132140, zgc:109996, c-fyn, zgc:86720, SLK, SYN, MGC45350, AI448320, AW552119, MGC115870, PKC
Clonality Monoclonal (2A10)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA
2 references available
Catalog no. ABIN966166
Quantity 0.1ml  (Variants)
Price 467.50 $   Plus shipping costs $45.00
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Additional Information
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Alternative name FYN
Gene ID 2534
Immunogen Purified recombinant fragment of human FYN expressed in E. Coli.
Isotype IgG1
Clone 2A10
Description This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Synonyms: SLK, SYN, MGC45350
Molecular Weight 61kDa

Application Details
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Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Ascitic fluid
Preservative 0.03% sodium azide.
Storage Store at 4°C, for long term storage, store at -20°C.
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Lu, Zhu, Cvrljevic et al.: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, 2009 (PubMed).

Brignatz, Paronetto, Opi et al.: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, 2009 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "FYN Oncogene Related To SRC, FGR, YES (FYN)", type "Antibodies"
Hosts Rabbit (48), Mouse (27), Goat (7)
Reactivities Human (65), Mouse (Murine) (45), Rat (Rattus) (28), Cow (Bovine) (26), Chicken (24), Dog (Canine) (24), Pig (Porcine) (24)
Applications Western Blotting (WB) (52), ELISA (25), Immunofluorescence (IF) (25), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (22), Immunoprecipitation (IP) (13), Immunohistochemistry (IHC) (8), Immunohistochemistry (Fixed) (IHC (fx)) (5), Functional Studies (Func) (4), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes N-Term (10), pTyr530 (9), AA 1-206 (4), AA 7-176 (4), C-Term (2), AA 1-197 (1), AA 1-537 (1), AA 23-216 (1), AA 35-51 (1), Internal Region (1), Middle Region (1), pThr2446 (1)