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Details for Product No. ABIN966167

FYN Oncogene Related To SRC, FGR, YES (FYN) antibody

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Antigen
Synonyms fyn, c-fyn, zgc:86720, SLK, SYN, p59-FYN, AI448320, AW552119, PKC, cfyn-a, im:6908851, si:dkey-119m7.5, zgc:109996
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), ELISA
Pubmed 2 references available
Catalog no. ABIN966167
Quantity 0.1 mL
Price
467.50 $   Plus shipping costs $45.00
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Immunogen Purified recombinant fragment of human FYN expressed in E. Coli.
Clone 2H8
Isotype IgG1
Purification Ascitic fluid
Alternative Name FYN
Background This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Synonyms: SLK, SYN, MGC45350
Molecular Weight 61kDa
Gene ID 2534
Application Notes Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Preservative Sodium azide
Storage 4 °C
Product cited in: Lu, Zhu, Cvrljevic et al.: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, 2009 (PubMed).

Brignatz, Paronetto, Opi et al.: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, 2009 (PubMed).

Alternatives for antigen "FYN Oncogene Related To SRC, FGR, YES (FYN)", type "Antibodies"
Hosts (79), (50), (10)
Reactivities (124), (83), (49), (28), (27), (27), (25), (2)
Applications (110), (58), (34), (23), (20), (17), (12), (12), (9), (6), (4), (3), (3), (2), (2), (2), (1)
Conjugates (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (21), (17), (7), (7), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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