Growth Differentiation Factor 15 (GDF15) (N-Term) antibody

Details for Product No. ABIN966197
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Antigen
Synonyms GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB, SBF
Epitope
N-Term
(42), (28), (12), (7), (5), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus)
(158), (55), (32), (8), (8)
Host
Rabbit
(141), (19), (7), (4), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(23), (17), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(155), (117), (35), (23), (15), (13), (10), (8), (7), (6), (3), (1), (1)
Pubmed 7 references available
Quantity 0.1 mg
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Catalog No. ABIN966197
466.13 $
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse GDF-15 (Growth Differentiation factor 15)
Alternative Name GDF-15
Background GDF-15 (Growth Differentiation factor 15) is a transforming growth factor beta superfamily member induced following liver injury. GDF-15 is a homodimer and disulfide-linked by similarity. GDF-15 is secreted and highly expressed in liver. GDF-15 belongs to the TGF-beta family.
Synonyms: macrophage inhibiting cytokine-1(MIC-1)
Restrictions For Research Use only
Product cited in: Zambrowicz, Abuin, Ramirez-Solis et al.: "Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14109-14, 2003 (PubMed).

Oxburgh, Chu, Michael et al.: "TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population." in: Development (Cambridge, England), Vol. 131, Issue 18, pp. 4593-605, 2004 (PubMed).

Noorali, Kurita, Woolcock et al.: "Dynamics of expression of growth differentiation factor 15 in normal and PIN development in the mouse." in: Differentiation; research in biological diversity, Vol. 75, Issue 4, pp. 325-36, 2007 (PubMed).

Zimmers, Jin, Gutierrez et al.: "Effect of in vivo loss of GDF-15 on hepatocellular carcinogenesis." in: Journal of cancer research and clinical oncology, Vol. 134, Issue 7, pp. 753-9, 2008 (PubMed).

Ding, Mracek, Gonzalez-Muniesa et al.: "Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes." in: Endocrinology, Vol. 150, Issue 4, pp. 1688-96, 2009 (PubMed).

Iguchi, Chrysovergis, Lee et al.: "A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2." in: Cancer letters, Vol. 282, Issue 2, pp. 152-8, 2009 (PubMed).

Cekanova, Lee, Donnell et al.: "Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice." in: Cancer prevention research (Philadelphia, Pa.), Vol. 2, Issue 5, pp. 450-8, 2009 (PubMed).

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