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Details for Product No. ABIN966221

Growth Factor Receptor-Bound Protein 7 (GRB7) (N-Term) antibody

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Antigen
Synonyms mKIAA4028, GRB7
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 4 references available
Catalog no. ABIN966221
Quantity 0.1 mg
Price
288.75 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7)(B47)
Purification Purified by antigen-specific affinity chromatography.
Alternative Name GRB7 (Growth factor receptor-bound protein 7)
Background The Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediated by the SH2 domain. The protein also binds to ERBB2 and interacts with RND1.
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Tanaka, Mori, Akiyoshi et al.: "Coexpression of Grb7 with epidermal growth factor receptor or Her2/erbB2 in human advanced esophageal carcinoma." in: Cancer research, Vol. 57, Issue 1, pp. 28-31, 1997 (PubMed).

Kishi, Sasaki, Akiyama et al.: "Molecular cloning of human GRB-7 co-amplified with CAB1 and c-ERBB-2 in primary gastric cancer." in: Biochemical and biophysical research communications, Vol. 232, Issue 1, pp. 5-9, 1997 (PubMed).

Tanaka, Mori, Akiyoshi et al.: "A novel variant of human Grb7 is associated with invasive esophageal carcinoma." in: The Journal of clinical investigation, Vol. 102, Issue 4, pp. 821-7, 1998 (PubMed).

Vayssière, Zalcman, Mahé et al.: "Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family." in: FEBS letters, Vol. 467, Issue 1, pp. 91-6, 2000 (PubMed).

Alternatives for antigen "Growth Factor Receptor-Bound Protein 7 (GRB7)", type "Antibodies"
Hosts (30), (8), (5)
Reactivities (42), (17), (14)
Applications (31), (16), (10), (4), (3), (3), (2), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (2), (2), (2), (2), (2), (1), (1), (1)
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