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MAPK11 antibody

MAPK11 Reactivity: Human, Mouse IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN966523
  • Target See all MAPK11 Antibodies
    MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))
    Reactivity
    • 66
    • 33
    • 22
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 81
    • 4
    • 3
    Rabbit
    Clonality
    • 83
    • 5
    Polyclonal
    Conjugate
    • 38
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MAPK11 antibody is un-conjugated
    Application
    • 82
    • 44
    • 29
    • 26
    • 26
    • 11
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to middle amino acid residues of human MAPK11 (Mitogen-activated protein kinase 11)
    Top Product
    Discover our top product MAPK11 Primary Antibody
  • Restrictions
    For Research Use only
  • Storage
    4 °C
  • Kumar, McDonnell, Gum, Hand, Lee, Young: "Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 533-8, (1997) (PubMed).

    Stein, Yang, Young, Janknecht, Hunter, Murray, Barbosa: "p38-2, a novel mitogen-activated protein kinase with distinct properties." in: The Journal of biological chemistry, Vol. 272, Issue 31, pp. 19509-17, (1997) (PubMed).

    Jiang, Chen, Li, Guo, Gegner, Lin, Han: "Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)." in: The Journal of biological chemistry, Vol. 271, Issue 30, pp. 17920-6, (1996) (PubMed).

  • Target
    MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))
    Alternative Name
    MAPK11 (MAPK11 Products)
    Synonyms
    ATMPK11 antibody, F22L4.10 antibody, F22L4_10 antibody, MAP kinase 11 antibody, zgc:86905 antibody, P38B antibody, P38BETA2 antibody, PRKM11 antibody, SAPK2 antibody, SAPK2B antibody, p38-2 antibody, p38Beta antibody, P38b antibody, Prkm11 antibody, Sapk2 antibody, Sapk2b antibody, p38beta antibody, p38beta2 antibody, p38b antibody, sapk2 antibody, prkm11 antibody, sapk2b antibody, mitogen-activated protein kinase 11 antibody, MAP kinase 11 antibody, mapk11 antibody, LOC9328118 antibody, MPK11 antibody, MAPK11 antibody, Mapk11 antibody, PTRG_02565 antibody
    Background
    MAPK11 (Mitogen-activated protein kinase 11) is involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. MAPK11 (Mitogen-activated protein kinase 11) phosphorylates preferentially transcription factor ATF2. MAPK11 (Mitogen-activated protein kinase 11) is activated by phosphorylation on threonine and tyrosine by MKK6. MAPK11 is inhibited by pyridinyl-imidazole related compounds. Highest levels of MAPK11 expression is in the brain and heart. MAPK11 is also expressed in the placenta, lung, liver, skeletal muscle, kidney and pancreas. The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases. MAPK11 is dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme. MAPK11 belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family and MAP kinase subfamily. MAPK11 contains 1 protein kinase domain.
    Synonyms: PRKM11, SAPK2 (Stress-activated protein kinase 2), p38-2 (Mitogen-activated protein kinase p38 beta), p38b (MAP kinase p38 beta)
    Pathways
    MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
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