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Neurofibromin 2 (NF2) antibody

Antigen

Neurofibromin 2 (NF2)

Synonyms ACN, SCH, BANF, NF2
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)

Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
3 references available
Catalog no. ABIN966568
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information

Alternative name Merlin
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Merlin around the phosphorylation site of serine 518 (R-L-SP-M-E).
Specificity Merlin (Ab-518) antibody detects endogenous levels of total Merlin protein.

Application Details

Application Notes WB: 1:500~1:1000.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Restrictions For Research Use only

Publications

Product Böhni, Hemmi, Aguet: "Signaling steps involving the cytoplasmic domain of the interferon-gamma receptor alpha-subunit are not species-specific." in: The Journal of biological chemistry, Vol. 269, Issue 20, pp. 14541-5, 1994 (PubMed).

Ratner, Bryan, Weber et al.: "Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19267-75, 2001 (PubMed).

Xiao, Gallagher, Shetler et al.: "The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression." in: Molecular and cellular biology, Vol. 25, Issue 6, pp. 2384-94, 2005 (PubMed).

Alternatives

Alternatives for antigen "Neurofibromin 2 (NF2)", type "Antibodies"
Hosts Rabbit (71), Goat (5), Mouse (1)
Reactivities Human (72), Mouse (Murine) (55), Rat (Rattus) (51), Cow (Bovine) (24), Dog (Canine) (24), Horse (Equine) (23), Pig (Porcine) (23), Chicken (7), Zebrafish (Danio rerio) (4), Cat (Feline) (1), Zebrafish (1)
Applications Western Blotting (WB) (51), ELISA (35), Immunofluorescence (IF) (29), Immunohistochemistry (IHC) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10), Immunoprecipitation (IP) (5), Immunocytochemistry (ICC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pSer518 (17), C-Term (5), pSer10,N-Term (3), Internal Region (2), Ser518 (2), AA 363-578 (1), N-Term (1), pSer10 (1), pSer553 (1), pThr582 (1)