Neurofibromin 2 (NF2) antibody

Details for Product No. ABIN966568
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Antigen
Synonyms NF2a, nf2, NF2, merlin, ACN, BANF, SCH, zgc:194620, zgc:194631
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(130), (88), (72), (25), (24), (24), (24), (5), (2), (1)
Host
Rabbit
(127), (8), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(109), (63), (33), (25), (24), (20), (10), (9), (3), (3)
Pubmed 3 references available
Quantity 100 μg
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Catalog No. ABIN966568
398.75 $
Plus shipping costs $45.00

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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Merlin around the phosphorylation site of serine 518 (R-L-SP-M-E).
Specificity Merlin (Ab-518) antibody detects endogenous levels of total Merlin protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name Merlin
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Böhni, Hemmi, Aguet: "Signaling steps involving the cytoplasmic domain of the interferon-gamma receptor alpha-subunit are not species-specific." in: The Journal of biological chemistry, Vol. 269, Issue 20, pp. 14541-5, 1994 (PubMed).

Ratner, Bryan, Weber et al.: "Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19267-75, 2001 (PubMed).

Xiao, Gallagher, Shetler et al.: "The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression." in: Molecular and cellular biology, Vol. 25, Issue 6, pp. 2384-94, 2005 (PubMed).

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