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Orthodenticle Homeobox 2 (OTX2) antibody

Antigen

Orthodenticle Homeobox 2 (OTX2)
Clonality Monoclonal (1H12G8B2)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
2 references available
Catalog no. ABIN966721
Quantity 0.1ml  (Variants)
Price 467.50 $   Plus shipping costs $45.00
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Additional Information
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Alternative name OTX2
Gene ID 5015
Immunogen Purified recombinant fragment of human OTX2 expressed in E. Coli.
Isotype IgG1
Clone 1H12G8B2
Description This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development.
Tissue specificity: Expressed in brain.
Synonyms: MCOPS5, MGC45000
Molecular Weight 32kDa

Application Details
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Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Ascitic fluid
Preservative 0.03% sodium azide.
Storage Store at 4°C, for long term storage, store at -20°C.
Restrictions For Research Use only

Publications
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Product Wyatt, Bakrania, Bunyan et al.: "Novel heterozygous OTX2 mutations and whole gene deletions in anophthalmia, microphthalmia and coloboma." in: Human mutation, Vol. 29, Issue 11, pp. E278-83, 2008 (PubMed).

Adamson, Shi, Wortham et al.: "OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas." in: Cancer research, Vol. 70, Issue 1, pp. 181-91, 2010 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Orthodenticle Homeobox 2 (OTX2)", type "Antibodies"
Hosts Rabbit (40), Mouse (8), Goat (1)
Reactivities Human (49), Rat (Rattus) (28), Mouse (Murine) (27), Chicken (23), Dog (Canine) (23), Cow (Bovine) (22), Horse (Equine) (19), Sheep (Ovine) (18), Rabbit (3), Xenopus laevis (2), Zebrafish (2), Cat (Feline) (1), Monkey (1)
Applications Western Blotting (WB) (33), Immunofluorescence (IF) (25), ELISA (22), Immunohistochemistry (IHC) (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Flow Cytometry (FACS) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)
Epitopes N-Term (3), Internal Region (2), AA 10-60 (1), C-Term (1)