PAK1/2/3 antibody (pThr402, pThr421, pThr423)

Catalog No. ABIN966798

Cited in 1 publication. The Rabbit Polyclonal anti-PAK1/2/3 antibody (ABIN966798) specifically detects PAK1/2/3 in IHC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for PAK1/2/3 antibody (pThr402, pThr421, pThr423) (ABIN966798)

Target: PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK1/2/3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-PAK1/2/3 Antibody

Binding Specificity: pThr402, pThr421, pThr423

Specificity: PAK1/PAK2/PAK3 (Phospho-Thr423/Thr402/Thr421) antibody detects endogenous levels of PAK1/PAK2/PAK3 only when phosphorylated at threonine 423/402/421.

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human PAK1 around the phosphorylation site of threonine 423 (R-S-TP-M-V).

Application Details

Application Notes: IHC: 1:50-1:100.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-PAK1/2/3 antibody (ABIN966798)

Wang, Mazumdar, Vadlamudi, Kumar: "P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium." in: The EMBO journal, Vol. 21, Issue 20, pp. 5437-47, (2002) (PubMed).

Target Details for PAK1/2/3

Target: PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))

Alternative Name: PAK1/PAK2/PAK3