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Progesterone Receptor (PGR) (AA 730-871) antibody

Details for Product No. ABIN966829
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Antigen
Synonyms PR, NR3C3, PR-A, PR-B, BB114106, 9930019P03Rik, ENSMUSG00000074510, XPR-1, pgr, xpr-2, LOC443444, PGR, pg, pr, gb:dq017620
Epitope
AA 730-871
(43), (40), (25), (16), (14), (13), (9), (9), (8), (8), (7), (7), (6), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(387), (72), (72), (14), (12), (7), (6), (3), (2), (2), (1), (1), (1)
Host
Mouse
(250), (161), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(8), (8), (8), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3)
Application
Western Blotting (WB), ELISA
(267), (151), (103), (96), (58), (54), (52), (37), (30), (6), (3), (1), (1)
Pubmed 4 references available
Quantity 0.1 mL
Options
Shipping to United States (Change)
Availability Will be delivered in 5 to 7 Business Days
Catalog No. ABIN966829
426.25 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Purified recombinant fragment of PGR (aa730-871) expressed in E. Coli.
Clone 8A11H1
Isotype IgG1
Purification Ascitic fluid
Alternative Name PGR
Background PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.
Synonyms: PR, NR3C3, PGR
Gene ID 5241
Application Notes Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Polo, José Galindo, Martínez et al.: "[Recommendations of the Study Group for Metabolic Alterations/Secretariat for the National AIDS Plan (GEAM/SPNS) on the management of metabolic and morphologic alterations in patients with HIV infection]." in: Enfermedades infecciosas y microbiología clínica, Vol. 24, Issue 2, pp. 96-117, 2006 (PubMed).

Tung, Abdel-Hafiz, Shen et al.: "Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2656-70, 2006 (PubMed).

Buser, Gass-Handel, Wyszomierski et al.: "Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 21, Issue 1, pp. 106-25, 2006 (PubMed).

Yin, Lin, Cheng et al.: "Progesterone receptor regulates Bcl-2 gene expression through direct binding to its promoter region in uterine leiomyoma cells." in: The Journal of clinical endocrinology and metabolism, Vol. 92, Issue 11, pp. 4459-66, 2007 (PubMed).

Hosts (250), (161), (1)
Reactivities (387), (72), (72), (14), (12), (7), (6), (3), (2), (2), (1), (1), (1)
Applications (267), (151), (103), (96), (58), (54), (52), (37), (30), (6), (3), (1), (1)
Conjugates (8), (8), (8), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3)
Epitopes (43), (40), (25), (16), (14), (13), (9), (9), (8), (8), (7), (7), (6), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN966829
426.25 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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