Phospholipase C, gamma 2 (PLCG2) antibody

Antigen: Phospholipase C, gamma 2 (PLCG2)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN966863

Additional Information

Alternative name: PLCgamma2

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human PLC2 around the phosphorylation site of tyrosine 753 (S-L-YP-D-V).

Specificity: PLC2 (Ab-753) antibody detects endogenous levels of total PLC2 protein.

Application Details

Application Notes: WB: 1:500~1:1000.

Concentration: 100ug/100ul.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: 0.02% Sodium Azide

Storage: Store at -20°C/1 year.

Restrictions: For Research Use only

Publications

Product: Suzuki-Inoue, Wilde, Andrews et al.: "Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 1023-9, 2004 (PubMed).

Kim, Sekiya, Poulin et al.: "Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 9986-99, 2004 (PubMed).